The scientific research groups of the Department:

  1. National Heart Program Research Group (NVKP_16-1-2016-0017 project)
    Leader: Dr. Edit Buzás, University Professor
  2. Extracellular Vesicles Research Group
    Leader: Dr. Edit Buzás, University Professor
    One of the major research areas of the Extracellular Vesicle Research Group is the role of post-synthetic protein- and lipid modifications (e.g. glycosylation, citrullination and oxidation) in the development of (auto)immune response (with special focus on rheumatoid arthritis). The other major research field of the group is the investigation of cell-derived membrane vesicles (exosomes, microvesicles and apoptotic bodies). We primarily focus on the role of membrane vesicles in autoimmunity and fetomaternal communication as well as on their stem cell biology and tumor immunology aspects.  The Inflammation Immunology/Membrane Vesicle Research Group participates in the Standardization of Pre-Analytical Variables of Plasma Microparticle Determination Workshop. The infrastructural background of membrane vesicle isolation is supported by Baross Gábor Infrastructural Development Program.
  3. National Heart Program Research Group (NVKP_16-1-2016-0017 project)
    Leader: Dr. Edit Buzás, University Professor
  4. Molecular Cancer Biology Research Group (NVKP_16-0007 project)
    Leader: Dr. Zoltán Wiener, Associate Professor
  5. Medical Genomics Research Group
    Leader: Dr. Csaba Szalai, University professor
    The Medical Genomics Research Group investigates the genomic and pharmacogenomic background and pathomechanism of the following multifactorial diseases: asthma, allergy and acute lymphoblastic leukemia. For our researches we use our asthma and childhood leukemia bio- and databanks, which are registered in the Hungarian NEKIFUT as strategic research infrastructures. In collaboration with the Department of Measurement and Information Systems of Budapest University of Technology and Economics, the group also participates in developing bioinformatic tools important for our researches.
  6. Chemotaxis Research GroupChemotaxis Research Group
    Leader: Dr. László Kőhidai, Associate Professor
    Main research fields investigated in Chemotaxis Research Group are
    (i) research on cell adhesion, chemotaxis and other basic cell physiological responses;  
    (ii) phylogeny of cell signaling - studies in ciliated model cells;
    (iii) characterization of 'Chemotaxome', the novel category of systems biology.
    An underlined, ongoing  project of the Research Group is to develop conjugates of drug-targeting available for different kinds of molecular delivery (chemotactic drug targeting) in tumors, atherosclerosis etc. The most significant models are unicellular eukaryotes (Tetrahymena pyriformis) as well as several mammalian tumor cell lines.   The Research Group is the host of the core facility of impedance based cell analytical research infrastructure (ECIS, xCELLignece) qualified as SKI by NEKIFUT/NKTH.  
  7. Experimental and Translational Immunomics Research GroupExperimental and Translational Immunomics Research Group
    Leader: Dr. Zoltán Pós, Associate Professor
    The Hungarian Academy of Sciences - Semmelweis Unversity ”Lendület” Experimental and Translational Immunomics Research Group, established in July 2012, conducts multidisciplinary research in the fields of immunology and genomics, with most of its efforts focused on the analysis of the recently discovered CD8+ T regional memory (Trm) cells, and related local immune responses. The group investigates these questions using automated isolation of organ-resident T memory and effector cells, genomic scale description of their organ-specific characteristics, and tracking in vivo T cell activity and movement, using both transgenic mouse models and human clinical samples.   
  8. Experimental Rheumatology Research GroupExperimental Rheumatology Research Group
    Leader: Dr. György Nagy, Associate Professor

 

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