CV
Birth: 1976
Professional qualifications:
- 2005: PhD degree, Semmelweis University, Budapest, Hungary. Thesis title: The role of histamine in the differentiation and functions of mast cells in vitro
- 2001: Teacher of biology (MSc), Eötvös Loránd University of Sciences, Budapest, Hungary
- 1999: Biologist (MSc, specialization: genetics), Eötvös Loránd University of Sciences, Budapest, Hungary
Education / Training list:
- 2015- : Semmelweis University, Department of Genetics, Cell and Immunobiology, assistant professor
- 2009-2015: Postdoctoral training in Prof. Kari Alitalo`s lab, Translational Cancer Biology Research Program, University of Helsinki, Finland
- 2006-2009: Head of the Semmelweis University Microarray Core Facility, Budapest, Hungary
- 2003-2009: Semmelweis University, Department of Genetics, Cell and Immunobiology, Budapest
- 2003: Visiting PhD student at the University of Bern, Institute of Pathology, Prof. Thomas Brunner`s research group, Switzerland
- 1999-2002: PhD student fellowship, Semmelweis University, Department of Genetics, Cell and Immunobiology
- 1997-1999: Hungarian Academy of Sciences, Institute of Enzymology, Budapest, scientific work as a student
- 1994-1999: Eötvös Loránd University of Sciences, Faculty of Natural Sciences, Budapest, Hungary
Academic fellowships, grants and awards:
- 2017-: Coordinator of a research grant by the National Research, Development and Innovation Office (NVKP_16)
- 2017- : ICGEB-CRP Early Career return Grant, International Centre for Genetic Engineering and Biotechnology, Italy
- 2016- : Research Grant by the National Research, Development and Innovation Office (Hungary, OTKA-NN)
- 2015- : Semmelweis University, Faculty of Medicine Startup Grant
- 2015- : János Bolyai Fellowship
- 2011-2012: Grant by the Sigrid Juselius Foundation (Finland) for foreign scientists
- 2011-2012: Research grant by the Sigrid Juselius Foundation (Finland), co-applicant
- 2009-2011: Marie-Curie Intra-European Fellowship (IEF), EU-FP7
- 2008: Arthur A. Hancock Young Investigator Award by the European Histamine Research Society
- 2008: Young Investigator Grant by Semmelweis University, Budapest
- 2007: Publication Award by Sigma-Aldrich Hungary
- 2006-2008: Research Grant by the Hungarian Ministry of Health (ETT)
Activities in education:
- 2016- : supervising PhD students at the Semmelweis University, School of PhD Studies
- 2015- : Teaching immunology, medical biology and genetics and genomics at the Semmelweis University
- 2011-2015: Co-supervising PhD students and undergraduate students at the University of Helsinki
- 2014: Co-author of the textbook “Az Immunológia alapjai” (Basics of Immunology), Semmelweis Publishing, Budapest, Hungary
- 2012-2013: Lectures at the PhD course “CancerBio Progress Report”, University of Helsinki
- 2006-2008: Lectures at the special course “Von den Molekülen bis zum Krankenbett” for German medical students, Semmelweis University, Hungary
- 2005: Genomics e-learning for the “Mindentudás Egyeteme” (University of All Knowledge), Budapest, Hungary
- 2004: Translating the textbook A. Malcolm Campbell and Laurie J. Heyer: Genomics, Proteomics and Bioinformatics (Chapters 4-9 and 12) into Hungarian, Medicina Publishing, Budapest, Hungary
- 2001-2008: Teaching cell biology and human genetics (medical biology) at Semmelweis University, Hungary for medical students (in Hungarian and German), lectures and practical courses
Professional visits:
- 2009-2015: Postdoctoral training in Prof. Kari Alitalo`s lab, University of Helsinki, Finland
- 2003: Prof. Thomas Brunner’s lab, Institute of Pathology, University of Bern, Bern, Switzerland
- 1998: Institute for Marine Research, Reykjavik, Iceland
Memberships:
- Associate member of the American Association for Cancer Research (AACR)
- Member of the International Society for Stem Cell Research (ISSRC)
- Member of the Hungarian Biochemical Society
- Member of the European Histamine Research Society (EHRS)
- Member of the Hungarian Society for Immunology
Scientific areas: tumor biology, stem cells, organoid technology, colorectal cancer, extracellular vesicles
Language skills: Hungarian, English, German
Publications
Selected publications:
- Kivelä R, Salmela I, Nguyen YH, Petrova TV, Koistinen HA, Wiener Z, Alitalo K (2016).
The transcription factor Prox1 is essential for satellite cell differentiation and muscle fibre-type regulation.
Nat Commun, 7, 13124. IF: 11,329.
- Wiener Z, Högström J, Hyvönen V, Band AM, Kallio P, Holopainen T, Dufva O, Haglund C, Kruuna O, Oliver G, Ben-Neriah Y, Alitalo K (2014).
Prox1 promotes expansion of the colorectal cancer stem cell population to fuel tumor growth and ischemia resistance.
Cell Rep, 8, 1943-56. IF: 7.207.
- Wiener Z, Band AM, Kallio P, Högström J, Hyvönen V, Kaijalainen S, Ritvos O, Haglund C, Kruuna O, Robine S, Louvard D, Ben-Neriah Y, Alitalo K (2014).
Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β.
Proc Natl Acad Sci USA, 111, E2229-36. IF: 9.809.
- Pribluda A, Elyada E, Wiener Z, Hamza H, Goldstein RE, Biton M, Burstain I, Morgenstern Y, Brachya G, Billauer H, Biton S, Snir-Alkalay I, Vucic D, Schlereth K, Mernberger M, Stiewe T, Oren M, Alitalo K, Pikarsky E, Ben-Neriah Y (2013).
A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism.
Cancer Cell, 24, 242-56. IF: 23.893.
- Elyada E, Pribluda A, Goldstein RE, Morgenstern Y, Brachya G, Cojocaru G, Snir-Alkalay I, Burstain I, Haffner-Krausz R, Jung S, Wiener Z, Alitalo K, Oren M, Pikarsky E, Ben-Neriah Y (2011).
CKIα ablation highlights a critical role for p53 in invasiveness control.
Nature, 470, 409-13. IF: 36.280.
Complete list of publications: MTMT, PubMed