Wiener Zoltan

Position: Associate Professor
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Room: NET 606
Phone: +36 1 210 2930 / 56432



Birth: 1976

Professional qualifications:

  • 2005: PhD degree, Semmelweis University, Budapest, Hungary. Thesis title: The role of histamine in the differentiation and functions of mast cells in vitro
  • 2001: Teacher of biology (MSc), Eötvös Loránd University of Sciences, Budapest, Hungary
  • 1999: Biologist (MSc, specialization: genetics), Eötvös Loránd University of Sciences, Budapest, Hungary

Education / Training list:

  • 2015- : Semmelweis University, Department of Genetics, Cell and Immunobiology, assistant professor
  • 2009-2015: Postdoctoral training in Prof. Kari Alitalo`s lab, Translational Cancer Biology Research Program, University of Helsinki, Finland
  • 2006-2009: Head of the Semmelweis University Microarray Core Facility, Budapest, Hungary
  • 2003-2009: Semmelweis University, Department of Genetics, Cell and Immunobiology, Budapest
  • 2003: Visiting PhD student at the University of Bern, Institute of Pathology, Prof. Thomas Brunner`s research group, Switzerland
  • 1999-2002: PhD student fellowship, Semmelweis University, Department of Genetics, Cell and Immunobiology
  • 1997-1999: Hungarian Academy of Sciences, Institute of Enzymology, Budapest, scientific work as a student
  • 1994-1999: Eötvös Loránd University of Sciences, Faculty of Natural Sciences, Budapest, Hungary

Academic fellowships, grants and awards:

  • 2017-: Coordinator of a research grant by the National Research, Development and Innovation Office (NVKP_16)
  • 2017- : ICGEB-CRP Early Career return Grant, International Centre for Genetic Engineering and Biotechnology, Italy
  • 2016- : Research Grant by the National Research, Development and Innovation Office (Hungary, OTKA-NN)
  • 2015- : Semmelweis University, Faculty of Medicine Startup Grant
  • 2015- : János Bolyai Fellowship
  • 2011-2012: Grant by the Sigrid Juselius Foundation (Finland) for foreign scientists
  • 2011-2012: Research grant by the Sigrid Juselius Foundation (Finland), co-applicant
  • 2009-2011: Marie-Curie Intra-European Fellowship (IEF), EU-FP7
  • 2008: Arthur A. Hancock Young Investigator Award by the European Histamine Research Society
  • 2008: Young Investigator Grant by Semmelweis University, Budapest
  • 2007: Publication Award by Sigma-Aldrich Hungary
  • 2006-2008: Research Grant by the Hungarian Ministry of Health (ETT)

Activities in education: 

  • 2016- : supervising PhD students at the Semmelweis University, School of PhD Studies
  • 2015- : Teaching immunology, medical biology and genetics and genomics at the Semmelweis University
  • 2011-2015: Co-supervising PhD students and  undergraduate students at the University of Helsinki
  • 2014: Co-author of the textbook “Az Immunológia alapjai” (Basics of Immunology),  Semmelweis Publishing, Budapest, Hungary
  • 2012-2013: Lectures at the PhD course “CancerBio Progress Report”, University of Helsinki
  • 2006-2008: Lectures at the special course “Von den Molekülen bis zum Krankenbett” for German medical students, Semmelweis University, Hungary
  • 2005: Genomics e-learning for the “Mindentudás Egyeteme” (University of All Knowledge), Budapest, Hungary
  • 2004: Translating the textbook A. Malcolm Campbell and Laurie J. Heyer: Genomics, Proteomics and Bioinformatics (Chapters 4-9 and 12) into Hungarian, Medicina Publishing, Budapest, Hungary
  • 2001-2008: Teaching cell biology and human genetics (medical biology) at Semmelweis University, Hungary for medical students (in Hungarian and German), lectures and practical courses

Professional visits:

  • 2009-2015: Postdoctoral training in Prof. Kari Alitalo`s lab, University of Helsinki, Finland
  • 2003: Prof. Thomas Brunner’s lab, Institute of Pathology, University of Bern, Bern, Switzerland
  • 1998: Institute for Marine Research, Reykjavik, Iceland


  • Associate member of the American Association for Cancer Research (AACR)
  • Member of the International Society for Stem Cell Research (ISSRC)
  • Member of the Hungarian Biochemical Society
  • Member of the European Histamine Research Society (EHRS)
  • Member of the Hungarian Society for Immunology

Scientific areas:
tumor biology, stem cells, organoid technology, colorectal cancer, extracellular vesicles

Language skills: Hungarian, English, German




Selected publications:

  • Kivelä R, Salmela I, Nguyen YH, Petrova TV, Koistinen HA, Wiener Z, Alitalo K (2016).
    The transcription factor Prox1 is essential for satellite cell differentiation and muscle fibre-type regulation.
    Nat Commun, 7, 13124. IF: 11,329.
  • Wiener Z, Högström J, Hyvönen V, Band AM, Kallio P, Holopainen T, Dufva O, Haglund C, Kruuna O, Oliver G, Ben-Neriah Y, Alitalo K (2014).
    Prox1 promotes expansion of the colorectal cancer stem cell population to fuel tumor growth and ischemia resistance.
    Cell Rep, 8, 1943-56. IF: 7.207.
  • Wiener Z, Band AM, Kallio P, Högström J, Hyvönen V, Kaijalainen S, Ritvos O, Haglund C, Kruuna O, Robine S, Louvard D, Ben-Neriah Y, Alitalo K (2014).
    Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β.
    Proc Natl Acad Sci USA
    , 111, E2229-36. IF: 9.809.
  • Pribluda A, Elyada E, Wiener Z, Hamza H, Goldstein RE, Biton M, Burstain I, Morgenstern Y, Brachya G, Billauer H, Biton S, Snir-Alkalay I, Vucic D, Schlereth K, Mernberger M, Stiewe T, Oren M, Alitalo K, Pikarsky E, Ben-Neriah Y (2013).
    A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism.
    Cancer Cell, 24, 242-56. IF: 23.893.
  • Elyada E, Pribluda A, Goldstein RE, Morgenstern Y, Brachya G, Cojocaru G, Snir-Alkalay I, Burstain I, Haffner-Krausz R, Jung S, Wiener Z, Alitalo K, Oren M, Pikarsky E, Ben-Neriah Y (2011).
    CKIα ablation highlights a critical role for p53 in invasiveness control.
    Nature, 470, 409-13. IF: 36.280.

Complete list of publications: 



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