Topic list


Immunology (AOKGEN737_1A)
3 credits

Please note that because of possible unforeseen changes of the virus situation, there might be changes to the regulations described below. In case of any changes we inform you on the startup page of the website of the department and by Neptun messages
Please read the general compulsory safety regulation on the startup page of the website

Course Description: This course provides a basic knowledge of the structure and mechanisms of the immune system, immunological responses in health and disease.

The immunology lectures and practices are kept online till further notice.
The attendance in the online practices (Zoom meetings) is compulsory.

According to the referred Rector's directive, you are obliged to provide the technical background for the practices. You have to be visible and audible by a camera and microphone switched on throughout the practices.

You'll find the zoom links of the lecture on Moodle, the zoom links of the practices on the homepage of the Department under „Zoom” headline. 

Spring: 2020/21
4th semester


Lectures (2*45 min / week)
Thursday 13:20-14:50
NET Selye János (Green) Lecture Hall

Practices / Seminars (1*70 min / week)

(Feb 15-19)

The role, processes, organs and cells of the immune system
ppt / Zoom video: video

The immune system in the lab
ppt / with voice: ppt

(Feb 22-26)

Principles of natural immunity
ppt / Zoom video: video

Methods based on antigen-antibody interactions I. Basic concepts related to diagnostic antibody
ppt / with voice: ppt

(Mar 1-5)

The complement system
ppt / Zoom video: video

Methods based on antigen-antibody interactions I. Immunoserology
ppt / with voice: ppt

(Mar 8-12)

Inflammation and acute phase reaction
ppt / Zoom video: video   video

Methods based on antigen-antibody interactions II. Immune-assays
ppt / with voice: ppt

(Mar 15-19)

Antigen, antigen presentation and MHCs
ppt / with voice: ppt

Methods based on antigen-antibody interactions III. Flow cytometry
ppt / with voice: ppt

(Mar 22-26)

Antigen receptors and their formation
ppt / with voice: ppt

Complement assays
ppt / with voice: ppt

Midterm test in Moodle
The first Moodle test is on the 26th March between 5:40-6:00 pm.
The test is available for 10 minutes after opening.

(Mar 29 - Apr 2)

T lymphocytes and cell-mediated immune response
ppt / with voice: ppt

Biological therapies I.
ppt / with voice: ppt

(Apr 5-9)

B lymphocytes and humoral immune response
ppt / with voice: ppt

Biological therapies II.
ppt / with voice: ppt

(Apr 12-16)

Immune response in infections;
ppt / Zoom video: video

Immunization and vaccination I.
ppt / with voice: ppt

(Apr 19-23)

Hypersensitivity reactions
ppt / Zoom video: video

Immunization and vaccination II.

(Apr 26-30)

Mucosal immunity
ppt / Zoom video: video

Hypersensitivity I.
ppt / with voice: video

(May 3-7)

Immunological tolerance; Natural and pathological autoimmunity
ppt / Zoom video: video

Hypersensitivity II-IV.
ppt / with voice: ppt

Midterm test in Moodle - Topics of 6th-12th week lectures and practices
On the 7th of May between 5:40-6:00 pm.
The test is available for 10 minutes after opening.

(May 10-14)

Antitumor immunity
ppt / Zoom video: video

Screening methods for autoantibodies
ppt / with voice: ppt

(May 17-21)

Immunology of transplantation and pregnancy immunity
ppt / Zoom video: video

HLA typing
Pre-exam consultation
ppt / with voice: ppt


Classes are cancelled on:
March 15th (Official holiday)
April 5th (Easter)
The order of the lectures and seminars may be subject to modifications.




Dear Students!

Please find below the join URLs of the online lecture and practices. All lectures and practices start as announced in the timetable of this semester. Please sign in to access the URL list!



Course information

Prerequisite subject: Molecular Cell Biology I, Medical Biochemistry II


Course Instructors and Contact Information:

Course instructor: Dr Marianna Csilla Holub, PhD
Office: NET 618
Office hours: As posted on the website of the Department
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Emails must include your full name and student number and have a descriptive subject line.
Expect an average response time of 2 business days. Email will not be checked on weekends or holidays.

Office hours: Because of the SARS-CoV-2 pandemic situation, educational administration is managed electronically. In case of questions and/or concerns better addressed in person, ask about the possibility of personal administration at the education administrator's phone number or e-mail address.

Education administrator: Némethné, Molnár Mária; office: NET 623, Phone: 210-2950, email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Lecturer and Chairman of the Department: Prof. Dr Edit Buzas, MD, DSc
Office: NET 717 - If you wish to discuss something with her, please email to set up an appointment.
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.



Attendance of a minimum of 75% of the practices is necessary for the end-term signature. The presence at the seminars (practices) are registered weekly, more than three absences (of any reason) from the seminars invalidate the semester. It is your task to keep track of your absences, they will only be summarized at the last week of the semester.
It is YOUR responsibility to get to class on time – more than 10 minutes delay means an absence. Plan to be on campus early on test days; transit and/or traffic issues happen but you cannot be given extra time to write. Plan to be at exams early.
The presence at the first midterms is the requirement for the validity of the semester. 

The final grade for the course will be based on the following:
Semi-final exam (date and time set by Neptun)
In case of personal attendance 90 min. long written test: 60 points.
In case of an online Moodle exam – 45 min. long test under Zoom supervision: 60 points

Your mark will be calculated as follows:
Students have to reach more than 50 % of the exam scores (31 out of 60) to pass.


Required Textbook:            

Abbas, Lichtmann, Pillai, Basic Immunology 5th Edition,Elsevier, 2015
Immunology seminars (e-book): (The user name and password is on the course datasheet of the Neptun.)
Lecture and practice ppt presentations and on Moodle system. (If you are not able to see the subject in Moodle, please contact the Education Administrator of the Department.)

Further Information

In the rooms of the NET building it is compulsory for everyone to wear a mask that covers both the nose and the mouse. Violation of this rule excludes a student from the practice/seminar or lecture and will have legal consequences according to the directive of the Rector and Chancellor (E/19/2020. (VIII. 28.). see

You will be responsible for material presented in class and associated textbook sections. The textbook is your resource and will help you understand this material. It contains many of the visuals presented in the lectures. Pay careful attention to the Figures and to the questions and guidelines for study at the end of each chapter.

Midterm expected through the Moodle system:

There are two written tests on the 6th and 12th weeks of the semester. The presence at the first midterm is the requirement for the validity of the semester.
The midterms will consist predominantly of multiple choice questions. The topics are based on the textbooks, the lectures, the practices and the ebook.
The success of the midterm is not a requirement to validate the semester, but based on their total scores, you receive bonus points for the semi-final exam according to the table below.

% of total scores of both midterms

Bonus points added to the exam test









Bonus points are only credited to those who have more than 50 % of the exam scores (31 out of 60).
Recording of the midterm tasks is NOT permitted. Students in violation of these policy may have legal action taken against them.
All test scores will be posted to Neptun when available. Do not email asking when grades will be posted or for your scores; these emails will not receive a response.
There is no opportunity to postpone the time of the midterm neither to improve the midterm result. Missed Midterm/Exam – General Policies: Students must have an urgent reason for missing a course test, such as illness, compassionate grounds, etc., Supporting documentation (e.g., attending physician’s statement) is required and must be shown up to the practice teacher (or course coordinator) within one week. Valid documentation for medical situations consists of a current “Attending Physician’s Statement” Only the current form will be accepted. If you do not use the current form you will be asked to return to your physician to have the correct form filled in. A note that simply says you were seen in the clinic will not be accepted. Any documentation should cover the date of the missed test.  If you have a valid reason for missing the original midterm, make up dates will be scheduled. We announce its date and place via a Neptun message.


Semi-final exam:

The semester ends up with a colloquium (semi-final exam; exam period: May 25, 2021 – July 9, 2021).
For taking the exam, students have to prove their identity by an official formal personal document with a photo (i.e. passport, student card).
The semifinal exam will have the same type of questions as the midterms but may include short answer, table fill-in, matching, drawing type questions and essay questions.
The topics are based on the textbooks and the lectures as well, so attending the latter ones greatly helps students to successfully prepare for the exam. At the exam, it is not sufficient to repeat memorized topics from the textbook and presentations, but you have to be able to synthesize and integrate your knowledge from different parts.
The exam dates will be published one month before the beginning of the exam period. Registration for the exam dates (or modifying the registration) can be arranged exclusively online by the students’ registration system (NEPTUN). If you want to change your exam day, first you have to cancel your earlier sign up. Since we have to book the exam rooms and Moodle virtual rooms in advance, we cannot change (increase) the maximum number of examinees. The announcement of the results takes 48 hours, depending on the number of examinees. Here we would also like to warn you  that in case of  postponing your  exam right to the end of the exam period, you may not be able to register to some of the subjects (which have Immunology  as a  prerequisite) of the next semester on time.
If you miss an exam, the second retake exam (and all others thereafter) can be taken upon payment of a retake fee. If you miss the exam for a valid reason you must request deferred standing. To request deferred standing you must submit a supporting documentation to the Students Administration Office of the Department (not to the Secretary) (NET 623) within 3 business days of the missed exam. Doctor’s notes are NOT sufficient for missed exams; you MUST have your doctor fill out the Attending Physician’s Statement (please make sure you are using the current version of the Attending Physician’s statement form – no other versions will be accepted). Exam missed without certification means the loss of one exam possibility.


Consultation in the exam period:

In the exam period the Department keeps an official 45 min consultation, once per week. The exact dates will be published on the website prior to the exam period.



Seminars in Immunology ebook: pdf

(Updated version 2015)



Exam information: doc

Exam topic list: doc






Dear Students!

Our institute will provide an online Zoom consultation on Monday, August 30 from 5:30 pm to 6:30 pm for Students taking the Immunology exam at the September exam dates.
Passcode: immun


Online consultations in the exam period: 

Dates and Zoom URLs: 

Please sign in to access dates and URLs!


Consultation for students who missed Immunology practices: 
17:40-18:50 Friday 21th of May
Zoom URL: Please sign in to access the URL! 





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