Keywords

• Definition of epigenetics; levels of epigenetic regulation related to transcription; types of epigenetic processes; mutual/putative aim of epigenesis
• DNA methylation; consequences of mC formation (nucleotide ratio, mutations, carcinogenesis); methyl donors; role of folate; CpG and CpG islands; CpG island and gene body and their methylation; DNMT1 and DNMT3, DNMT3L; alternative promoter use and alternative splicing in gametogenesis; MBD and MeCP2; Rett-syndrome; TET-enzymes, hydroxyl-methyl cytosine (5-hmC); 5-caC and 5-fC and their role in gene regulation
• Histone modifications; histone code; frequently modified amino acids of histones; HAT and HDAC; HMT and HDM; interactions between the modified histones; bivalent histone modification in ES cells; alternative histone variants
• Chromatin remodelling; polycomb and trithorax group of proteins; their interaction with  modified histones and DNA; CTCF and cohesion and functional organization of chromatin, TADs
• Post-translational modifications; citrullination and disease; histone citrullination
• Post transcriptional RNA modifications; epitranscriptomics
• Types of non-coding RNAs; genomic localization; tsRNA, siRNA and RNAi; microRNAs (pri-miR and pre-RNA) and lncRNAs (Xist and lincRNA); gene silencing through these RNAs; types of interactions leading to gene expression modification
• Position effect; silencing of transposons and retroviral elements; IAP and agouti and yellow colour; food supplementation;
• Imprinting; parental conflict theory; IGF2 and IGF2R; bipedality as an evolutionary explanation; loss of imprinting (LOI); inprinting diseases; Prader-Willi and Angelman syndromes; differentially methylated regions (DMRs); Beckwith-Wiedemann and Silver-Russel syndromes; UDP as a cause of imprinting diseases; imprinting centres (ICs), insulators;
• X-chromosome inactivation; random and imprinted; dose compensatory mechanisms; XIC and XIST; counting and choice; Tsix; MSUD; skewed X inactivation and diseases/phenomena related to it; territorial arrangement of X inactivation; evolutionary and tissue specific differences in X inactivation; escape and escapees,; DNA methylation and characteristic histone modifications;
• Paramutation; transvection; mitotic  bookmarking; RNA and protein transfer from parents to offspring;
• DNA methylation during the early stages of embryogenesis; pluripotency factors in X inactivation and in reprogramming; ES and iPS cells in epigenetic research; epigenetic events in reprogramming; cloning; ART and increased Beckwith–Wiedemann birth rate; Transgenerational epigenesis; Dutch famine; role of diet, calory restriction, endocrine disruptors and maternal behaviour;
• Cancer epigenetics; CpG island hypermethylation; gene body hypomethylation; genetic and epigenetic interactions; genome instability; CpG island shore methylation; TSG and oncogene silencing and activation; cell cycle regulatory and DNA repair proteins as targets of epimutations; HDAC and DNMT inhibitors: problem of specificity and targeting resistance;
• Epigenetics of aging; telomeres and telomerase in aging; subtelomeric and telomeric epigenetic features; twin studies; aging regulatory network;
• Maternal behaviour and its transgenerational epigenetic consequences; mental diseases (ADHD, schizophrenia and psychosis) and epigenetics; social status, stress and their epigenetic effects;