Topic list

Basic Immunology (FOKGEN037_1A)
(3 credits)

Course Description: This course provides a basic knowledge of the structure and mechanisms of the immune system, immunological responses in health and disease. 

Topic list and Schedule
Fall 2019/20
5th Semester


Lectures (2*45 min. / week)
Monday 13:30 - 15:10
NET Selye (Green) Lecture Hall

Practices / Seminars (1*45 min. / week)

(Sept 9-13)

The roles, processes, organs and cells of the immune system

Basic terms; the immune system in the lab

(Sept 16-20)

Principles of natural immunity
ppt   pdf

Methods based on antigen-antibody interactions I. Immunoserology
ppt   pdf

(Sept 23-27)

The complement system; inflammation and acute phase reaction
ppt   pdf

Methods based on antigen-antibody interactions II. 
ppt   pdf

(Sept 30 - Oct 4)

Antigen, antigen presentation and MHCs

Methods based on antigen-antibody interactions III. Flow cytometry
ppt   pdf

(Oct 7-11)

Antigen receptors and their formation

Complement assays
ppt   pdf

(Oct 14-18)

T lymphocytes and cell-mediated immune response

Immunization and vaccination I.
ppt   pdf

(Oct 21-25)

B lymphocytes and humoral immune response


Immunization and vaccination II.
ppt   pdf

(Oct 28-31)

Immune response in infections;
ppt   pdf

Biological therapies I.
ppt   pdf

(Nov 4-8)

Midterm exam (written)

Biological therapies II.
ppt   pdf

(Nov 11-15)

Mucosal immunity
ppt   pdf

Hypersensitivity I.
ppt   pdf

(Nov 18-22)

Hypersensitivity reactions
ppt   pdf

Hypersensitivity II-IV.
ppt   pdf

(Nov 25-29

Immunological tolerance; natural and pathological autoimmunity
ppt   pdf

Screening methods for autoantibodies
ppt   pdf

(Dec 2-6)

Antitumor immunity
ppt   pdf

HLA typing
ppt   pdf

(Dec 9-13)

Immunology of transplantation
ppt   pdf

Case studies / Pre-exam consultation

Classes are cancelled on October the 23rd, and on November the 1st.
The order of the lectures and seminarss may be subject to modifications. 


Course information

Prerequisite subject:
Anatomy (Maxillofacial Anatomy) IV., Biochemistry, Molecular and Cellbiology III.; Medical and Dental Physiology II


Course Instructors and Contact Information:

Course instructor: Dr Marianna Csilla Holub, PhD
Office: NET 618
Office hours: As posted on the website of the Department
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Emails must include your full name, student number and faculty and have a descriptive subject line.
Expect an average response time of 2 business days. Email will not be checked on weekends or holidays.
Email is not a substitute for office hours. Some questions and/or concerns are better addressed in person and you will be asked to come to office hours.

Lecturer and Chairman of the Department: Prof. Dr Edit Buzas, MD, DSc
Office: NET 717 - If you wish to discuss something with her, please email to set up an appointment.


Attendance of a minimum of 75% of the practices is necessary for the end-term signature. The presence at the seminars (practices) are registered weekly, more than three absences from the seminars invalidate the semester as well.
It is YOUR responsibility to get to class on time – more than 10 minutes delay means an absence. Plan to be on campus early on test days; transit and/or traffic issues happen but you cannot be given extra time to write. Plan to be at exams early.

The final grade for the course will be based on:
Semi-final exam (date and time set by Neptun) – 90 min. long written test: 60 points

Your mark will be calculated as follows:
Students have to reach more than 50 % of the exam scores (31 out of 60) to pass.


Required Textbook:            
KUBY Immunology :  Kuby Immunology 7th Edition. J. Owen, J. Punt and S. Stranford. W.H. Freeman and Company Publishers. • New York • 2013
Immunology seminars (e-book): (The user name and password is on the course datasheet of the Neptun.)
Lecture and practice ppt presentations 

Further Information
You will be responsible for material presented in class and associated textbook sections. The textbook is your resource and will help you understand this material. It contains many of the visuals presented in the lectures. Pay careful attention to the Figures and to the questions and guidelines for study at the end of each chapter.

Midterm: The presence at the midterm is the requirement for the validity of the semester. Recording of the midterm tasks is NOT permitted. Students in violation of these policy may have legal action taken against them.
The midterms will consist predominantly of multiple choice but include short answer, table fill-in, matching and drawing type questions. The semifinal exam will have the same type of questions as the midterms and may have essay questions.
All test grades will be posted to Neptun when available. Do not email asking when grades will be posted or for your grade; these emails will not receive a response.
There is no opportunity to postpone the time of the midterm neither to improve the midterm result. Missed Midterm/Exam – General Policies: Students must have an urgent reason for missing a course test, such as illness, compassionate grounds, etc., Supporting documentation (e.g., attending physician’s statement) is required and must be shown up to the practice teacher (or course coordinator) within one week. Valid documentation for medical situations consists of a current “Attending Physician’s Statement” Only the current form will be accepted. If you do not use the current form you will be asked to return to your physician to have the correct form filled in. A note that simply says you were seen in the clinic will not be accepted. Any documentation should cover the date of the missed test. . If you have a valid reason for missing the original midterm, make up dates will be scheduled. We announce its date and place via a Neptun message.
For taking the midterm (or exam), students have to prove their identity by an official formal personal document with a photo (i.e. passport, driving license).

Semi-final exam:
The topics are based on the textbooks and the lectures, so attending the latter ones greatly helps students to successfully prepare for the exam. At the exam, it is not sufficient to repeat memorized topics from the textbook and presentations, but you have to be able to synthesize and integrate your knowledge from different parts.
The exam dates will be published one month before the beginning of the exam period. Registration for the exam dates (or modifying the registration) can be arranged exclusively online by the students’ registration system (NEPTUN). If you want to change your exam day, first you have to cancel your earlier sign up. Since we have to book the exam rooms in advance, we cannot change (increase) the maximum number of examinees. The announcement of the results takes two-four working days, depending on the number of examinees. Here we would also like to warn you that in case of postponing your exam right to the end of the exam period, you may not be able to register to some of the subjects (which have Immunology as a prerequisite) of the next semester on time.
If you miss an exam, the second retake exam (and all others thereafter) can be taken upon payment of a retake fee. The receipt has to be presented to the examiner at the beginning of the exam. If you miss the exam for a valid reason you must request deferred standing. To request deferred standing you must submit a supporting documentation to the Students Administration Office of the Department (not to the Secretary) (NET 623) within 3 business days of the missed exam. Doctor’s notes are NOT sufficient for missed exams; you MUST have your doctor fill out the Attending Physician’s Statement (please make sure you are using the current version of the Attending Physician’s statement form – no other versions will be accepted). Exam missed without certification means the loss of one exam possibility.

Consultation in the exam period:
In the exam period the Department keeps an official 45 min consultation, once per week. The exact dates will be published on the website prior the exam period.

***: Due to the change Academic and Examination Rules in August 2019, the followings can differ partly from that in the Calendar.



Seminars in Immunology ebook: pdf

(Updated version 2015)



Exam topic list: doc 






Immunology consultations (in the NET building)

30 December (Monday) 10.00 L15
6 January (Monday) 10.00 L15
13 January (Monday) 10.00 L15
20 January (Monday) 10.00 L15
27 January (Monday) 10.00 L15

The consultation lasts for maximum 70 minutes. If there are no students present at the beginning of the consultation, it will be cancelled.






The user name and password are published in the NEPTUN.

Deputy Chairman:
Dr. SZALAI, Csaba
+36 1 210 2930 / 56236

Course coordinators:
Cell Science / Biology:

Dr. LÁNG, Orsolya
+36 1 210 2930 / 56251

Dr. HOLUB, Marianna
+36 1 210 2930 / 56234

Genetics and Genomics:
Dr. HEGYESI, Hargita
+36 1 210 2930 / 56326

Academic (Neptun) administration:
+36 1 210 2950
+36 1 210 2930 / 56253

Office hours of course coordinators >>>

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