Topic list

Basic Immunology” (GYGENIMUE1A-00)
3  credits


Course Description: This course provides a basic knowledge of the structure and mechanisms of the immune system, immunological responses in health and disease.

Topic list and Schedule
Fall: 2018/19 1st semester


Lectures (2*45 min / week)
Monday, 10:05 – 11:35, NET Sz6

(Sept 10 - 14)

Role, processes, organs and cells of the immune system

(Sept 17 - 21)

Principles of natural immunity

(Sept 24 - 28)

The complement system

(Oct 1 - 5)

Inflammation and acute phase reaction

(Oct 8 - 13)

Antigen, antigen presentation and MHCs

Saturday: Antigen receptors and their formation

(Oct 15 - 19)

T lymphocytes and cell-mediated immune response

(Oct 24 - 26)


(Oct 29 - 31)

B lymphocytes and humoral immune response

(Nov 5 - 10)

Immune response in infections; immonodeficiencies

(Nov 12 - 16)

Hypersensitivity reactions

(Nov 19 - 23)

Immunological tolerance; natural and pathological autoimmunity

(Nov 26 - 30)

Antitumor immunity

(Dec 3 - 7)

Transplantation and pregnancy immunity

(Dec 10 - 14)


Lecture is cancelled on October 22nd – INSTEAD of it, lecture is held on September the 13th, Saturday.
The order of the lectures and seminars may be subject to modifications.


Course information


Prerequisite subject:
Biology II., Anatomy, Medical Terminology

Course Instructors and Contact Information:

Course instructor: Dr Marianna Csilla Holub, PhD
Office: NET 618
Office hours: As posted on the website of the Department
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Emails must include your full name, student number and faculty and have a descriptive subject line.
Expect an average response time of 2 business days. Email will not be checked on weekends or holidays.
Email is not a substitute for office hours. Some questions and/or concerns are better addressed in person and you will be asked to come to office hours.

Lecturer and Chairman of the Department: Prof. Dr Edit Buzas, MD, DSc
Office: NET 717 - If you wish to discuss something with her, please email to set up an appointment.



According to the Academic and Examination Rules (17§ 7-8.), students must visit at least 75% of the classes: Attendance of a minimum of 75% of the lectures is necessary for the end-term signature. The presence at the lectures are registered weekly, more than three absences invalidates the semester.
It is YOUR responsibility to get to class on time – more than 10 minutes delay means an absence. Plan to be at exams early.



Required Textbook:            
Abbas, Lichtmann, Pillai, Basic Immunology 5th Edition,Elsevier, 2015, eBook ISBN: 9780323400145, eBook ISBN: 9780323400114, eBook ISBN: 9780323400152, Paperback ISBN: 9780323390828
Lecture ppt presentations


Further Information

You will be responsible for material presented in class and associated textbook sections. The textbook is your resource and will help you understand this material. It contains many of the visuals presented in the lectures. Pay careful attention to the Figures and to the questions and guidelines for study at the end of each chapter.

Semi-final exam:
The topics are based on the textbooks and the lectures, so attending the latter ones greatly helps students to successfully prepare for the exam. At the exam, it is not sufficient to repeat memorized topics from the textbook and presentations, but you have to be able to synthesize and integrate your knowledge from different parts. The retake exam can be taken no sooner than on the 3rd day after the former exam.
The exam dates will be published one month before the beginning of the exam period. Registration for the exam dates (or modifying the registration) can be arranged exclusively online by the students’ registration system (NEPTUN). If you want to change your exam day, first you have to cancel your earlier sign up. Please, consider the registration deadlines for the exams (48 hrs before the beginning of the exam). Since we have to book the exam rooms in advance, we cannot change (increase) the number of examinees. The announcement of the results takes two-four working days, depending on the number of examinees. Here we would also like to warn you  that in case of  postponing your  exam right to the end of the exam period, you may not be able to register to some of the subjects (which have Immunology  as a  prerequisite) of the next semester on time.
For taking the exam, students have to prove their identity by an official formal personal document with a photo (i.e. passport, driving license).
The semifinal exam will consist predominantly of multiple choice but include short answer, table fill-in, matching and drawing type questions and may have essay questions.
All exam grades will be posted to Neptun when available. Do not email asking when grades will be posted or for your grade; these emails will not receive a response.
If you miss an exam, the second retake exam (and all others thereafter) can be taken upon payment of a retake fee. The receipt has to be presented to the examiner at the beginning of the exam. If you miss the exam for a valid reason you must request deferred standing. To request deferred standing you must submit a supporting documentation to the Students Administration Office of the Department (NET 623)  (not to the Secretary) within 3 business days of the missed exam. Doctor’s notes are NOT sufficient for missed exams; you MUST have your doctor fill out the Attending Physician’s Statement (please make sure you are using the current version of the Attending Physician’s statement form – no other versions will be accepted).
Recording of the exam tasks is NOT permitted. Students in violation of these policy may have legal action taken against them.


Seminars in Immunology ebook: pdf

(Updated version 2015)



Exam topic list: doc





Immunology consultations (in the NET building) – 2nd semester of 2018/19

17 December (Monday) 13.00 L15-16
2 January (Wednesday) 10.00 L15-16
7 January (Monday) 11.00 L15-16
14 January (Monday) 11.00 L15-16
21 January (Monday) 11.00 L15-16
28 January (Monday) 11.00 L15-16

The consultation lasts for maximum 70 minutes. If there are no students present at the beginning of the consultation, it will be cancelled.






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