Basic Immunology (FOKOGEN347_1A)
3 credits
Fall: 2022/23 3rd semester 

Topic list


(2*45 min with 10 mins break)
Tuesday 14:20-16:00 
EOK Hári Lecture Hall

Practices / Seminars (1*45 min/week)

(Sept 5-9)

The roles, processes, organs and cells of the immune system

The immune system in the lab

(Sept 12-16)

Principles of natural immunity

Methods based on antigen-antibody interactions. Basic concepts related to diagnostic antibody

(Sept 19-23)

The complement system
Inflammation and acute phase reaction

Methods based on antigen-antibody interactions I. Immunoserology

(Sept 26-30)

Antigen, antigen presentation and MHCs

Methods based on antigen-antibody interactions II. Immune-assays

(Oct 3-7)

Antigen receptors and their formation

Methods based on antigen-antibody interactions III. Flow cytometry

(Oct 10-15)

Midterm test
Midterm test in Moodle (1st-5th week lectures and practices) - in the time of 6th week lecture, with personal attendance.
11th October, Tuesday
On your own device: mobile phone, laptop, iPad
You have 12 minutes to fulfill the test including 15 points.
doc   doc

T lymphocytes and cell-mediated immune response

Complement assays

(Oct 17-21)

B lymphocytes and humoral immune response

Biological therapies I.

(Oct 24-28)

Immune response in infections;

Biological therapies II.

(Nov 2-4)


Immunization and vaccination

(Nov 7-11)

Mucosal immunity

HLA typing

(Nov 14-18)

Hypersensitivity reactions

Hypersensitivity I.

(Nov 21-25)

Midterm test
Midterm test in Moodle  - in the time of 12th week lecture, with personal attendance.
22nd November, Tuesday
On your own device: mobile phone, laptop, iPad
You have 12 minutes to fulfill the test including 15 points.

Immunological tolerance; natural and pathological autoimmunity

Hypersensitivity II-IV.

(Nov 28 - Dec 2)

Immunology of transplantation

Screening methods for autoantibodies

(Dec 5-9)

Antitumor immunity

Pre-exam consultation

The order of the lectures and seminars may be subject to modifications. 



Course information

This course provides a basic knowledge of the structure and mechanisms of the immune system, immunological responses in health and disease.

Prerequisite subject:
Cell Science, Biochemistry I


Course Instructors and Contact Information:

Course instructor: Dr Marianna Csilla Holub, PhD
Office: NET 618
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Emails must include your full name, faculty and student number and have a descriptive subject line.
Expect an average response time of 2 business days. Email will not be checked on weekends or holidays.

Office hours: Educational administration is managed online. In case of questions and/or concerns better addressed in person , ask about the possibility of personal administration at the education administrator's phone number or e-mail address.

Education administrator: Némethné Molnár Mária; office: NET 623, Phone: 210-2950, email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Lecturer and Chairman of the Department: Prof. Dr Edit Buzas, MD, DSc

Office: NET 717 - If you wish to discuss something with her, please email to set up an appointment.



Attendance of a minimum of 75% of the practices is necessary for the end-term signature. The presence at the practices (seminars) are registered weekly, more than three absences (of any reason) invalidate the semester.

It is YOUR responsibility to get to class on time – more than 5 minutes delay means an absence. Plan to be on campus early on test days; transit and/or traffic issues happen but you cannot be given extra time to write. Plan to be at exams early.

The presence at the midterm is NOT the requirement for the validity of the semester.


Lecture and practice ppt presentations
Required Textbook:            
Abbas, Lichtmann, Pillai, Basic Immunology 6th Edition,Elsevier, 2019
Immunology seminars (e-book) (The user name and password is on the course datasheet of the Neptun.)


Midterm expected through the Moodle system:

There are two Moodle written tests on the 6th and 12th weeks of the semester. The presence at the midterm is NOT the requirement for the validity of the semester.

The midterms will consist multiple choice questions. The topics are based on the textbooks, the lectures, the practices and the ebook.

The success of the midterm is not a requirement to validate the semester, but based on their total scores, you receive bonus points for the semi-final exam according to the table below.

% of total scores

Bonus points added to the exam test









Bonus points are only credited to those who have passed the exam. (have 55 % of the exam scores or more, achieved at least grade 2).

Recording of the midterm tasks is NOT permitted. Students in violation of these policy may have legal action taken against them.

All test scores will be posted to Neptun when available. Do not email asking when grades will be posted or for your scores; these emails will not receive a response.

There is no opportunity to postpone the time of the midterm neither to improve the midterm result.


Semi-final exam: 

The semester ends up with a colloquium (semi-final exam; exam period: December 12, 2022 - January 27, 2023).

Semi-final exam (date and time set by Neptun) – written Moodle test, personal attendance.

The exam dates will be published one month before the beginning of the exam period.

Registration for the exam dates (or modifying the registration) can be arranged exclusively online by the students’ registration system (NEPTUN). If you want to change your exam day, first you have to cancel your earlier sign up. Since we have to book the exam rooms in advance, we cannot change (increase) the maximum number of examinees.

For taking the exam, students have to prove their identity by an official formal personal document with a photo (i.e. passport, student card, driving license). According to the Study and examination rules: "Students are not allowed to take an examination without identifying themselves. Students may identify themselves at the examination by any suitable document, which contains both a signature and a picture. If the student is unable to verify his/her identity, a “did not appear” note has to be recorded on the examination sheet and in NEPTUN, which does not reduce the number of exam opportunities, yet the student is obliged to pay an exam administration fee, which is specified in the Regulations of Refunds and Allowances."

According to this, the photo of any ID, presented on a phone is not suitable for proving identity.

The final grade for the course will be based on the following: 
see details in Exam information

The topics are based on the textbooks and the lectures, so attending the latter ones greatly helps students  to successfully prepare for the exam. In the exam it is not enough to reproduce the topics of the textbook and presentations, but you have to be able to synthesize and integrate the knowledge from different parts.

The announcement of the results may take two working days, depending on the number of examinees.


Missed Exam – General Policies: Students must have an urgent reason for missing a course test, such as illness, compassionate grounds, etc., If you miss the exam for a valid reason you must request deferred standing. To request deferred standing you must submit a supporting documentation to the Students Administration Office of the Department (not to the Secretary) (NET 623) within 3 business days of the missed exam. Supporting documentation (e.g., attending physician’s statement) is required and must be shown up to the practice teacher (or course coordinator) within one week. Valid documentation for medical situations consists of a current “Attending Physician’s Statement” (please make sure you are using the current version of the Attending Physician’s statement form – no other versions will be accepted). Only the current form will be accepted. If you do not use the current form you will be asked to return to your physician to have the correct form filled in. A note that simply says you were seen in the clinic will not be accepted. Any documentation should cover the date of the missed test. Exam missed without certification means the loss of one exam possibility.

Consultation in the exam period:

In the exam period the Department holds an official 45 min ZOOM consultation, once per week. The exact dates will be published on the website prior the exam period.



Seminars in Immunology ebook: pdf

(Updated version 2015)




Exam information and topics: doc (updated: 01.12.2022)

Pop-up questions: doc 







In the exam period the Department keeps an official 45 min consultation, once per week. 



Zoom URL

12 December

Meeting ID: 971 3861 9554
Passcode: 407837

19 December


9 January


16 January


23 January


30 January


6 Februar


The consultation lasts for 45 minutes. If there are no students present in the first 10 minutes, the consultation is cancelled.  







The user name and password are published in the NEPTUN.

Course coordinators:

Dr. LAJKÓ, Eszter

Dr. HOLUB, Marianna
+36 1 210 2930 / 56234

Genetics and Genomics:
Dr. HEGYESI, Hargita
+36 1 210 2930 / 56326

Academic (Neptun) administration:
+36 1 210 2950
+36 1 210 2930 / 56253

Office hours of course coordinators >>>

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