Dear Students,

In accordance with the 77/2022. (III. 4.) Government Decree, from 7th March 2022 it is not mandatory to wear a mask covering the nose and mouth, however, based on epidemiological statistics, our Department recommends the use of masks in small educational rooms (practice rooms). 

Basic Immunology (FOKOGEN347_1A)
2 credits
Fall: 2021/22 3rd semester


Please note that because of possible unforeseen changes of the virus situation, there might be changes to the regulations described below. In case of any changes we inform you on the startup page of the website of the department and by Neptun messages.

Course Description: This course provides a basic knowledge of the structure and mechanisms of the immune system, immunological responses in health and disease.

Topic list


Lectures (2*45 min/week)
Tuesday 14:40 - 16:20
NET Selye (Green) Lecture Hall

Practices / Seminars (1*45 min/week)

(Sept 6-10)

The roles, processes, organs and cells of the immune system
ppt / Zoom video: video

The immune system in the lab

(Sept 13-17)

Principles of natural immunity
ppt / with voice: ppt

Methods based on antigen-antibody interactions. Basic concepts related to diagnostic antibody

(Sept 20-24)

The complement system
ppt / with voice: ppt

Methods based on antigen-antibody interactions I. Immunoserology

(Sept 27 - Oct 1)

Inflammation and acute phase reaction
ppt / with voice: ppt

Methods based on antigen-antibody interactions II. immune-assays

(Oct 4-8)

Antigen, antigen presentation and MHCs
ppt / with voice: ppt

Methods based on antigen-antibody interactions III. Flow cytometry

(Oct 11-15)

Midterm test in Moodle (1st-5th week lectures and practices)
The first Moodle exam is on the 14th October between 6.30-6.50 pm.
You have 10 minutes to fulfill the test including 15 points.

Antigen receptors and their formation
ppt / with voice: ppt

Complement assays

(Oct 18-22)

T lymphocytes and cell-mediated immune response
ppt / with voice: ppt

Biological therapies I.

(Oct 25-29)

B lymphocytes and humoral immune response
ppt / with voice: ppt

Biological therapies II.

(Nov 2-5)

Immune response in infections;
ppt / with voice: ppt

Immunization and vaccination

(Nov 8-12)

Mucosal immunity
ppt / with voice: ppt

HLA typing

(Nov 15-19)

Hypersensitivity reactions
ppt / with voice: ppt

Hypersensitivity I.

(Nov 22-26)

Midterm test in Moodle (6th-11th week lectures and 5th-10th week practices)
The second Moodle exam is on the 25th November between 6.30-6.50 pm.
You have 10 minutes to fulfill the test including 15 points.

Immunological tolerance; natural and pathological autoimmunity
ppt / with voice: video

Hypersensitivity II-IV.

(Nov 29 - Dec 3)

Antitumor immunity
ppt / with voice: video

Screening methods for autoantibodies

(Dec 6-10)

Immunology of transplantation
ppt / with voice: video

Case studies / Pre-exam consultation

The order of the lectures and seminars may be subject to modifications. 



Course information

Prerequisite subject:
Cell Science, Biochemistry I


Course Instructors and Contact Information:

Course instructor: Dr Marianna Csilla Holub, PhD
Office: NET 618
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Emails must include your full name, faculty and student number and have a descriptive subject line.
Expect an average response time of 2 business days. Email will not be checked on weekends or holidays.

Office hours: Because of the SARS-CoV-2 pandemic situation, educational administration is managed electronically. In case of questions and/or concerns better addressed in person , ask about the possibility of personal administration at the education administrator's phone number or e-mail address.

Education administrator: Némethné Molnár Mária; office: NET 623, Phone: 210-2950, email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Lecturer and Chairman of the Department: Prof. Dr Edit Buzas, MD, DSc

Office: NET 717 - If you wish to discuss something with her, please email to set up an appointment.


of a minimum of 75% of the practices is necessary for the end-term signature. The presence at the practices (seminars) are registered weekly, more than three absences (of any reason) invalidate the semester.

It is YOUR responsibility to get to class on time – more than 10 minutes delay means an absence. Plan to be on campus early on test days; transit and/or traffic issues happen but you cannot be given extra time to write. Plan to be at exams early.

The presence at the midterm is NOT the requirement for the validity of the semester.


Lecture and practice ppt presentations
Required Textbook:            
Abbas, Lichtmann, Pillai, Basic Immunology 5th Edition,Elsevier, 2015
Immunology seminars (e-book) (The user name and password is on the course datasheet of the Neptun.)

Other Information

In the rooms of the NET building it is highly recommended to wear a mask that covers both the nose and the mouse. 


Midterm expected through the Moodle system:

There are two written tests on the 6th and 12th weeks of the semester. The presence at the midterm is NOT the requirement for the validity of the semester.
The midterms will consist multiple choice questions. The topics are based on the textbooks, the lectures, the practices and the ebook.
The success of the midterm is not a requirement to validate the semester, but based on their total scores, you receive bonus points for the semi-final exam according to the table below.

% of total scores

Bonus points added to the exam test









Bonus points are only credited to those who have more than 50 % of the exam scores.
Recording of the midterm tasks is NOT permitted. Students in violation of these policy may have legal action taken against them.
All test scores will be posted to Neptun when available. Do not email asking when grades will be posted or for your scores; these emails will not receive a response.
There is no opportunity to postpone the time of the midterm neither to improve the midterm result. 

Semi-final exam: The semester ends up with a colloquium (semi-final exam; exam period: December 13, 2021 - January 28, 2022). 
Semi-final exam (date and time set by Neptun) – written test.

The exam dates will be published one month before the beginning of the exam period.
Registration for the exam dates (or modifying the registration) can be arranged exclusively online by the students’ registration system (NEPTUN). If you want to change your exam day, first you have to cancel your earlier sign up. Since we have to book the exam rooms in advance, we cannot change (increase) the maximum number of examinees.
For taking the exam, students have to prove their identity by an official formal personal document with a photo (i.e. passport, student card, driving license).

The final grade for the course will be based on the following:

Students must first complete a pop-up test and score at least 13 points out of 15 multiple-choice questions in order to continue the exam. The possible MC questions of the pop-up test are published on the website along the semester.
The exam test is a 45 points test, including multiple choice questions, may include short answer, table fill-in, matching, drawing type questions and essay questions.
The exam test will have the same type of questions as the midterms but may include short answer, table fill-in, matching, drawing type questions and may have essay questions.
The topics are based on the textbooks and the lectures as well, so attending the latter ones greatly helps students  to successfully prepare for the exam. At the exam, it is not sufficient  to repeat memorized topics from the textbook and presentations, but you have to be able to synthesize and integrate your knowledge from different parts.
Bonus points are added to tests over 50 % of the exam test scores.
The announcement of the results may take two working days, depending on the number of examinees.

Missed Exam – General Policies: Students must have an urgent reason for missing a course test, such as illness, compassionate grounds, etc., If you miss the exam for a valid reason you must request deferred standing. To request deferred standing you must submit a supporting documentation to the Students Administration Office of the Department (not to the Secretary) (NET 623) within 3 business days of the missed exam. Supporting documentation (e.g., attending physician’s statement) is required and must be shown up to the practice teacher (or course coordinator) within one week. Valid documentation for medical situations consists of a current “Attending Physician’s Statement” (please make sure you are using the current version of the Attending Physician’s statement form – no other versions will be accepted). Only the current form will be accepted. If you do not use the current form you will be asked to return to your physician to have the correct form filled in. A note that simply says you were seen in the clinic will not be accepted. Any documentation should cover the date of the missed test. Exam missed without certification means the loss of one exam possibility.

Consultation in the exam period:

In the exam period the Department keeps an official 45 min consultation, once per week. The exact dates will be published on the website prior the exam period.



Seminars in Immunology ebook: pdf

(Updated version 2015)



Exam topics:  doc

Exam pop-up test:  doc





In the exam period the Department keeps an official 45 min consultation, once per week. 

Immunology consultations in the exam period:

Dec 13     16:00-17:00
Dec 20 16:00-17:00
Dec 27 16:00-17:00
Passcode: 177732
Jan 3 16:00-17:00
Jan 10 16:00-17:00
Passcode: 177732
Jan 17 16:00-17:00
Jan 24 16:00-17:00
Passcode: 177732






The user name and password are published in the NEPTUN.

Deputy Chairman:
Dr. SZALAI, Csaba
+36 1 210 2930 / 56236

Course coordinators:
Cell Science / Biology:

Dr. LÁNG, Orsolya
+36 1 210 2930 / 56251

Dr. HOLUB, Marianna
+36 1 210 2930 / 56234

Genetics and Genomics:
Dr. HEGYESI, Hargita
+36 1 210 2930 / 56326

Academic (Neptun) administration:
+36 1 210 2950
+36 1 210 2930 / 56253

Office hours of course coordinators >>>

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