Lectures (Lecturer: Tóth S.)

Wednesday 16.30-18.00,  NET L16

1st week

(10. Sept.)

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2nd week

(17. Sept.)

Timeline of epigenetics; levels of epigenetic changes; targets of epigenetics

3rd week

(24. Sept.)

DNA methylation; de novo and maintenance methylation; Dnmt interactions

4th week

(01. Oct.)

Histone modifications; histone code; histone modifying enzymes

5th week

(08. Oct.)

Polycomb and trithorax complexes; Methylated DNA binding proteins; chromtatin remodelling

6th week

(15. Oct.)

Transposons, and non-coding RNAs in epigenetic regulation; RNAi; chromatin remodelling; Paramutation, transvection

7th week

(22. Oct.)

Genome imprinting

8th week

(29. Nov.)

X inactivation and skewed X inactivation: their connection to DNA methylation

9th week

(05. Nov.)

Epigenetic changes during early development and gameto-genesis; epigenetic consequences of cloning and ART

10th week

(12. Nov.)

Transgenerational epigenetics; epigenetics of endocrine disruptors; maternal behaviour and its epigenetic consequences

11th week

(19. Nov.)

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12th week

(26. Nov.)

Role of epigenetics in carcinogenesis; epigenetic therapy in cancer; Mitotic bookmarking

13th week

(03. Dec.)

Epigenetics in aging and autoimmunity

14th week

(10. Dec.)

Epigenetic changes in diseases of the central nervous system
Small molecules, clock genes and intermediate metabolism in epigenetic regulation